How frequently must the IACUC evaluate the animal care program?

The correct answer regarding the frequency at which the IACUC must evaluate the animal care program is bi-annually. According to the Animal Welfare Act and the associated regulations, the IACUC is required to conduct a thorough review of the institution's program for animal care and use every six months. This ensures that the policies, procedures, and practices for animal care are being followed and that they meet the required standards for humane and ethical treatment.

Evaluating the animal care program bi-annually provides a systematic opportunity for the IACUC to identify any areas needing improvement, address any emerging concerns regarding animal welfare, and ensure compliance with relevant regulations. Such frequent evaluations help maintain a high standard of care for the animals involved in research and education and support institutions in meeting their ethical obligations.

The other options suggest evaluation frequencies that do not align with federal requirements, which could jeopardize the integrity of the animal care program and the institution's compliance with regulatory standards.