If the IACUC withholds approval, what must be included in the notification?

When the IACUC withholds approval for a research proposal or animal use protocol, it is essential to provide clear communication to the investigator about the reasons for this decision. Including both the reasons for the decision and an opportunity for the investigator to respond is crucial in maintaining transparency and fostering good communication between the IACUC and the research team. This practice aligns with ethical standards and regulatory requirements that emphasize the importance of providing feedback and allowing for a dialogue to potentially address any concerns.

The opportunity to respond allows the investigator to address the IACUC's concerns, clarify any misunderstandings, and possibly revise the protocol to meet the committee's requirements. This two-way communication is vital in ensuring that animal welfare standards are upheld, and it encourages a cooperative relationship between researchers and the oversight committee.