Is a formal Post Approval Monitoring program required by PHS Policy?

The correct answer indicates that a formal Post Approval Monitoring (PAM) program is not explicitly required by the Public Health Service (PHS) Policy. While the PHS Policy emphasizes the importance of oversight of animal care and use programs, it does not mandate the establishment of a formal PAM program as a component of compliance.

Instead, the PHS encourages institutions to implement effective oversight mechanisms to ensure the humane and ethical treatment of animals used in research, which can include aspects of PAM. However, institutions have the flexibility to determine how best to achieve compliance with the principles of the policy.

It's also essential to recognize that while not required by PHS Policy, many institutions choose to implement PAM programs as a best practice to enhance their IACUC activities. These programs support ongoing compliance by monitoring animal research activities after IACUC approval, ensuring adherence to approved protocols, and facilitating a culture of transparency and accountability in animal care.

Therefore, the absence of a formal requirement in the PHS Policy for such a program leads to the conclusion that the answer provided is appropriate within the context of the question.