PHS Policy __________ an occupational health and safety program for PHS-assured institutions.

The PHS Policy specifically mandates an occupational health and safety program for institutions that have PHS assurance. This requirement reflects the significance of maintaining the health and safety of personnel working with animals in research settings. By making such a program compulsory, the PHS aims to ensure that institutions take appropriate measures to protect the welfare of their employees and uphold safe working environments. This includes not only addressing physical hazards but also considering factors related to mental and emotional well-being.

The other choices represent varying degrees of recommendation or guidance rather than a definitive requirement. While recommendations and outlines are valuable in providing frameworks for best practices, they do not carry the same level of obligation as a requirement. Therefore, the term "requires" accurately captures the imperative nature of the PHS Policy regarding occupational health and safety programs in assured institutions.