What does the PHS Policy state about the use of the Guide for the Care and Use of Laboratory Animals by institutions receiving federal funding for research?

The choice that indicates the PHS Policy's requirements regarding the Guide for the Care and Use of Laboratory Animals is correct in stating that institutions receiving federal funding must use the Guide as a foundational element for developing and implementing their animal care and use programs. The PHS Policy mandates that any institution that receives Public Health Service funds must ensure its animal care and use protocols align with the standards set forth in the Guide.

This is essential as the Guide provides comprehensive guidelines on the humane treatment and proper care of laboratory animals, thereby promoting their welfare in research settings. Implementing the Guide ensures that institutions adhere to ethical considerations and regulatory compliance necessary for federally funded research, enhancing animal welfare and scientific integrity.

The other choices tend to understate the obligation imposed by the PHS Policy, as they imply a more voluntary or suggestive relationship with the Guide rather than the clear requirement that institutions must adhere to it for their programs.