What is required before conducting surgery regarding antinociception?

The requirement to confirm antinociception at a surgical plane of anesthesia is crucial before performing surgery. Antinociception refers to the process of blocking the detection of a painful or harmful stimulus by the nervous system, which is vital during surgery to ensure that the animal does not experience pain. Achieving a proper surgical plane of anesthesia guarantees that the animal is fully unconscious and unable to feel pain, creating a humane environment for the procedure.

This consideration is essential in veterinary and biomedical research settings both for ethical reasons and to ensure accurate experimental outcomes, as pain can interfere with physiological responses and recovery. Ensuring that antinociception is confirmed means that the animal is adequately prepared for the surgery, which is aligned with the principles of humane treatment and welfare in research settings. The correct evaluation of anesthesia and pain control also prevents complications during the procedure and contributes to better post-operative recovery.