What is the minimum number of designated reviewers required for a protocol using designated-member review?

The minimum number of designated reviewers required for a protocol using designated-member review is one. This approach allows for efficiency in the review process, as it enables a smaller group of designated members from the IACUC to assess protocols, rather than requiring a full committee meeting for every review.

Having just one designated reviewer simplifies the process, making it quicker for the research team to receive feedback and for the IACUC to manage their workload. This method is particularly beneficial for protocols that may be considered low risk or that align closely with previously reviewed and approved procedures.

Thus, the correct understanding of designated-member review supports the principle of balancing regulatory oversight with the practical needs of research, ensuring that protocols can be evaluated promptly while still maintaining ethical standards in animal research.