What is the role of the Institutional Official regarding animal-use projects?

The role of the Institutional Official (IO) is to ensure that all animal-use projects comply with the directives and regulations established by the Institutional Animal Care and Use Committee (IACUC). This includes overseeing that the institution adheres to federal, state, and local laws as well as ethical standards related to animal care and use. The IO is responsible for providing the necessary resources and support to the IACUC and ensuring that the institution's research activities align with the IACUC's evaluations and recommendations.

While the IO plays a critical role in the administration and compliance aspects of animal research, they do not independently approve research projects, oversee the entire animal-care facility, or monitor animal welfare without IACUC input. Their primary focus is to facilitate compliance and uphold the integrity of animal research practices rather than taking on more hands-on operational roles. This ensures a collaborative framework where animal welfare, regulatory compliance, and institutional policies are aligned for the benefit of both the research community and the animals involved.