What should the selection of analgesics and anesthetics reflect?

The selection of analgesics and anesthetics should reflect professional veterinary judgment and the research protocol because it ensures that the welfare of the animals is prioritized while also adhering to the scientific aims of the study. Professional veterinary judgment is crucial as veterinarians have the expertise to assess the appropriate types and dosages of analgesics and anesthetics based on the species involved, the specific procedures being performed, and the overall health status of the animals.

Incorporating the research protocol is also key, as it outlines the specific objectives and methods of the study, ensuring that the chosen analgesics and anesthetics align with the experimental design while maintaining compliance with ethical standards. This approach balances the need for valid research outcomes with the obligation to minimize pain and distress in research animals, reflecting the principles of the 3Rs (Replacement, Reduction, Refinement) in animal research.

Other choices, while they may have some relevance, do not adequately address the comprehensive and nuanced considerations necessary in selecting analgesics and anesthetics. For instance, only focusing on research requirements might overlook the ethical considerations regarding animal welfare. Relying on personal preferences of researchers could lead to inconsistent and potentially harmful choices that do not align with best practices in veterinary care. Recommendations from the industry can provide useful insights