Which action is NOT permitted by the IO according to Animal Welfare Regulations and PHS policy?

The action that is not permitted by the Institutional Official (IO) according to Animal Welfare Regulations and PHS policy is the ability to approve an activity involving animals. This is because the responsibility for the approval of animal use protocols lies specifically with the Institutional Animal Care and Use Committee (IACUC). The IACUC is tasked with ensuring the humane and ethical treatment of animals used in research, which includes reviewing and approving research proposals that involve animal subjects.

The role of the IO is primarily one of oversight and administration, ensuring that the institution complies with all relevant laws and regulations regarding animal research. While the IO has significant authority, their function does not include the direct approval of animal studies; that power rests with the IACUC, which evaluates the scientific, ethical, and welfare aspects of the proposed work.

Understanding the division of responsibilities between the IO and the IACUC is crucial for maintaining compliance with regulations and ensuring the integrity of animal research programs.