Which body requires the reporting of uncorrected significant deficiencies?

The requirement to report uncorrected significant deficiencies is held by both the USDA (United States Department of Agriculture) and the federal funding agency. This dual responsibility ensures that animal research institutions adhere to stringent standards for animal welfare and regulatory compliance.

The USDA oversees the enforcement of the Animal Welfare Act and requires that any significant deficiencies in animal care and use, which have not been corrected, are reported. Simultaneously, federal funding agencies, which provide grants for research involving animals, demand accountability and transparency regarding compliance with animal welfare standards. By requiring institutions to report such deficiencies, both bodies promote a culture of continuous improvement in animal care and research practices, thereby protecting animal welfare and upholding the integrity of the research process. This combined oversight is crucial in ensuring adherence to regulations and standards.

In contrast, focusing solely on one authority—either the USDA or the federal funding agency—would not provide a complete picture of the compliance landscape, as both entities have roles in ensuring that animal research is conducted ethically and responsibly. The IACUC, while critical in reviewing and overseeing animal care practices, does not have the authority to mandate reporting; rather, its role is to assess protocols and ensure compliance with regulations.