Which combination is required for IACUC members according to PHS policy?

The combination required for Institutional Animal Care and Use Committee (IACUC) members according to PHS policy includes a veterinarian, a nonaffiliated member, a scientist, and a nonscientist. This diverse composition ensures that the committee can comprehensively review animal care and use protocols from multiple perspectives, adhering to ethical standards and regulations.

Having a veterinarian on the IACUC is essential as they provide expertise on animal health and welfare issues. The inclusion of a scientist brings in the necessary background in research methodologies involving animal models. A nonscientist contributes a broader community perspective, ensuring that considerations beyond scientific elements are taken into account. The inclusion of a nonaffiliated member, who does not have a direct stake in the institution, helps maintain objectivity and can represent public interests in animal welfare and ethical considerations.

This balance is critical for oversight, as it allows for informed and impartial evaluations of research proposals involving animals, fulfilling both ethical and regulatory responsibilities.