Which of the following statements is false concerning prolonged restraint of animals?

The statement that prolonged restraint can be justified as a convenience for the research staff is false because ethical guidelines in animal research prioritize the welfare of the animals over logistical considerations for staff convenience. The justification for using any restraint must be based on a scientific rationale that directly relates to the study's objectives, not on the ease or convenience it might provide to researchers. Animal care ethics emphasize the need to minimize stress and discomfort for the animals involved in research.

In contrast, the other statements highlight important principles regarding the use of restraint in research settings. Using the least restrictive method aligns with the ethical approach of minimizing animal suffering while still achieving valid scientific outcomes. Additionally, ensuring that the period of restraint is the minimum necessary reinforces the commitment to animal welfare. Lastly, stating that restraint should not be considered a normal method of housing establishes a clear distinction between humane housing practices and temporary measures that are only used when absolutely necessary for specific research objectives.