Which of these is not part of the acronym used by the entity overseeing animal research safety?

The acronym that is commonly associated with the oversight of animal research safety involves organizations and policies that help ensure humane and ethical treatment of animals used in research. The National Research Council (NRC) is indeed involved in the development of guidelines and recommendations concerning animal care and use, but it is not part of the direct oversight framework itself.

In contrast, the other choices refer to entities that are actively involved in the regulatory and oversight mechanisms for animal research safety. For instance, OLAW (Office of Laboratory Animal Welfare) is part of the National Institutes of Health and oversees compliance with animal welfare regulations. Similarly, PHS (Public Health Service) provides support for the humane care and use of animals in research funded by the NIH. IRAC (Institutional Animal Care and Use Committee) plays a key role by being the institution-level committee responsible for ensuring compliance with federal regulations and guidelines related to animal research.

Therefore, NRC does not directly comprise the oversight framework but rather contributes to the broader context of animal research safety practices, making it the option that does not fit within the core acronym used for direct animal research oversight.