Which two institutional administrators are specifically dealt with in regulations?

The correct answer focuses on the specific roles outlined in animal welfare regulations, particularly the Institutional Official (IO) and the Chief Executive Officer (CEO). The IO is a crucial figure who has the authority and responsibility for overseeing the institution's animal care and use program, ensuring compliance with applicable laws, regulations, and guidelines. This role is significant as the IO must ensure that all animal research conducted at the institution meets ethical standards and federal regulations.

The CEO also plays a vital role as they are responsible for the overall governance and operation of the institution, which includes the welfare of animals used in research. The CEO delegates authority to the IO but is ultimately accountable for the organization’s compliance and policies pertaining to animal care and use.

While other options mention key administrative positions, they do not have direct regulations tied to the oversight of animal research programs in the way that the IO and CEO do. Positions like the COO, CFO, Provost, and Dean, while important in their own right, do not have regulatory responsibilities specifically concerning animal research compliance defined in federal regulations. Thus, the role of the IO and CEO together specifically aligns with the oversight and administrative governance outlined in animal welfare regulations, making this choice the correct answer.