Who has the authority to approve a course of action following an IACUC investigation?

A majority vote of a quorum at a convened IACUC meeting is the correct response because IACUCs operate under a system of collaborative decision-making. When an investigation occurs, it involves evaluating potential concerns related to the care and use of animals in research. This process is intended to be thorough and inclusive, allowing for diverse perspectives and expertise to contribute to the final decision-making.

The presence of a quorum ensures that a sufficient number of members are involved in the decision, reflecting a balanced and representative process. This democratic approach is in line with the ethical standards and regulatory requirements governing animal research, as it promotes accountability and transparency.

While the IACUC Chairperson plays an important role in facilitating meetings and guiding discussions, the authority to approve actions following an investigation rests with the collective committee rather than any individual member. The Institutional Official's authority also does not negate the IACUC's decisive role, as this official is typically responsible for making sure that the institution complies with IACUC recommendations, rather than acting independently of the committee's findings. Therefore, the decision-making process appropriately involves the majority of the IACUC members to ensure that all voices are heard and considered.