Who has the legal authority to sign the USDA registration form of a research institution?

The correct choice is the Institutional Official. This individual has the legal authority to sign the USDA registration form on behalf of the research institution. The Institutional Official is typically someone in an administrative position who oversees the institution's animal care and use program, ensuring compliance with federal regulations and institutional policies related to animal research.

The Institutional Official's role is crucial as they are responsible for the overall integrity of the institution's program and are accountable to both the institution and regulatory bodies. This authority encompasses a wide range of responsibilities, including the signing of forms that attest to compliance with the Animal Welfare Act and other relevant laws.

While the other positions, such as the Animal Facility Director, Animal Facility Manager, and Attending Veterinarian, play essential roles in the animal care and use program, they do not possess the legal authority to sign the USDA registration form. Their responsibilities may include day-to-day management, oversight of animal care standards, and veterinary care, but the final accountability and regulatory compliance lie with the Institutional Official.