Who is responsible for ensuring that the amendments are reviewed before implementation?

The IACUC, or Institutional Animal Care and Use Committee, is the body responsible for overseeing the ethical and humane treatment of animals in research settings. Its role includes reviewing and approving amendments to animal care and use protocols before they can be implemented. This oversight ensures that any proposed changes comply with relevant regulations and ethical standards, protecting both the welfare of the animals and the integrity of the research.

In an IACUC context, amendments may involve changes to animal housing, experimental procedures, or care protocols. To maintain compliance with federal regulations, institutional policies, and ethical considerations, these amendments must be vetted by the IACUC to assess their potential impact on animal welfare and scientific validity. Only after the committee grants approval can researchers proceed with the changes.

This process emphasizes the IACUC's critical function in maintaining oversight and ensuring adherence to the ethical guidelines that govern animal research, reflecting their commitment to animal welfare and regulatory compliance.