Who is responsible for the ethical treatment of animals in research at an institution?

The ethical treatment of animals in research at an institution is primarily the responsibility of the Institutional Official (IO). The IO is typically a high-ranking individual within the institution who holds ultimate authority and accountability for compliance with animal care and use regulations. This role encompasses ensuring that the institution adheres to ethical standards and federal regulations regarding animal research.

The IO not only oversees the activities of the Institutional Animal Care and Use Committee (IACUC) but also ensures that appropriate resources and support are allocated to uphold the standards of animal care. This includes fostering a culture of ethical consideration throughout the institution and endorsing the decisions and recommendations made by the IACUC.

While the IACUC Chair and the Attending Veterinarian play significant roles in the oversight and direct care of animals, respectively, it is the Institutional Official who holds the ultimate responsibility for ethical compliance. The Chief Executive Officer may have a similar role but is not always directly involved in the specific oversight of animal research ethics. Thus, the role of the Institutional Official is critical in maintaining the ethical treatment of animals in a research environment.