Who must be notified of IACUC decisions to approve, withhold approval, or require modifications?

When the IACUC makes decisions regarding the approval, withholding of approval, or requiring modifications of a research proposal, it is essential that both the principal investigator (PI) and the institution are promptly notified. This communication ensures that the PI is aware of the IACUC's stance, which is crucial for compliance with ethical standards and regulatory requirements governing animal research.

The institution, as the entity responsible for the research environment, needs to be informed to maintain oversight and ensure that the necessary actions are taken based on the IACUC's decisions. This notification also allows the institution to implement any changes requested by the IACUC or to begin the process for any appeals if the IACUC withholds approval.

Involving both the PI and the institution in the communication loop is vital for maintaining transparency and accountability in the research process, fostering a collaborative environment where animal welfare concerns are prioritized while addressing the research objectives.